Effective pain relievers discovered in animal studies often fail in clinical trials, but testing drugs in human tissues first may overcome this problem.
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Human Tissue in Pain Research — a Promising Fix for a “Leaky” Drug Development Pipeline?
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Recent Highlights
ANNOUNCEMENT: New Podcast on Neuropathic Pain
Airing Pain has recently released a new podcast on neuropathic pain (Airing Pain 116) that was facilitated by the neuropathic pain special interest group (NeuPSIG) of the International Association for the Study of Pain (IASP). Read here for more information about the podcasts.
ANNOUNCEMENT: IASP's Proposed New Definition of Pain Released for Comment
An IASP Definition of Pain Task Force has just released a new proposed definition of pain and is seeking public comments. We invite the RELIEF community of readers to submit written feedback for consideration by the Task Force. Learn more here, and submit a comment today here.
ANNOUNCEMENT: A New Classification System of Chronic Pain Approved by World Health Organization
The World Health Organization (WHO) has adopted ICD-11, the latest revision of its International Classification of Diseases, including a new classification system for chronic pain developed by an International Association for the Study of Pain (IASP) Task Force. The decision was made at the World Health Assembly on 25 May 2019. The new system will transform patient care and pain research worldwide. To learn more, read the IASP press release here, along with a previous Pain Research Forum feature article here.
Neurons Go Haywire During Pain From Nerve Injury
A new study uses nerve cells from patients with spinal tumors to identify changes in the nervous system underlying neuropathic pain.
I Feel Your Pain: Emotional “Mirror Neurons” in the Brain Respond to Pain in the Self and in Others
A new animal study shows that nerve cells in a part of the brain called the anterior cingulate cortex become active when a rat undergoes pain or watches another rat experience pain.
Physiotherapy for Pain and All That Jazz: A Chat with Romy Parker
Pain management expert Romy Parker discusses the importance of interdisciplinary teams to help manage chronic pain, the crucial role of physiotherapists on those teams, and her hopes for the future of pain management.
How Sleep Affects Pain
A recent brain imaging study shows that sleep deprivation increases pain sensitivity. -
Pain…What Pain? Newly Discovered Genetic Mutations in a Woman Who Feels No Pain
A recent case report describes a woman with a novel combination of mutations in a key enzyme in the endocannabinoid system.